The World's Leading Skincare Glossary, brought to you by Lesielle

The 1st Customized Skincare System that Adapts to YOUR Changing Needs


INCI: Pichia Ferment Lysate Filtrate

What is Pichia Ferment Lysate Filtrate?

Filtered liquid derived from the fermentation of Pichia pastoris.

Pichia pastoris is a methylotrophic yeast.

An humectant, Skin condition agent and Skin protectant.

Use & Benefits:

Aids in skin moisture retention, during harsh weather conditions it can draw moisture towards the skin and prevent it from escaping. This proactive barrier gives the skin a soft smooth feel which in turn prevents skin flakes or dry patches due to loss of moisture which can lead to an impaired skin structure.

Can help improve signs of aging, and help with firming and restoring skin luster to give a more youthfull appearance and glow. This is achieved by restoring the DEJ, while also helping reduce inflammation.

Personalized & Adaptive skincare system

Create your own custom skincare and  adapt it to your skin changes

How to create your own Personalized Skincare with Lesielle?

Icons of the lesielle custom skin care system

Step 1: Select a nourishing base compatible with your skin, and your desired moisturization level

Step 2: Complete your treatment with up to four active ingredients for consistent and occasional use.

Step 3: Insert your base and up to four actives ingredients into your Lesielle device to produce a fresh single dose of face cream on demand when you need it.

Complete your routine with a cleanser and other complimentary products and accessories.


Don't you know what Base and Actives your skin needs?

Take our personalized skincare quiz.

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The skincare system for an ever evolving skin, using recognized active ingredients with scientifically proven efficacy to create treatment tailored to each day's State of Skin. 

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