What are Actives?

Actives are the ingredients that rejuvenate and repair your skin. Different actives have different effects, from conditioning acne-prone skin to anti-aging and more.

Combining science and technology
to create freshly blended skin care

Ingredients with
proven efficacy

made fresh

for any need at
any time

Get the actives to accomplish your goals

Lesielle actives are divided into six ranges depending on your skincare goals. Ingredients from different ranges are combined with a base by the Lesielle S skin care, giving you a fresh, bespoke and all-in-one cream.

Ingredients like retinol which visibly correct and repair signs of aging, improving the appearance of your skin.

Ingredients like vitamin E which help prevent the signs of aging and improve the overall appearance of your skin.

Ingredients like vitamin C that give your face a glow, improving skin tone and visibly correcting marks and pigmentation.

Ingredients like salicilic acid that smooth your skin, making it uniform and correcting imperfections such as blackheads, enlarged pores and acne.

Ingredients like hyaluronic acid that provide your skin with protection against the environment and external agents.

Ingredients like bisabolol that provide a soothing effect to help your skin return to its natural state.

Clean beauty, toxin-free

Made in Europe

Cruelty-free ingredients

Dermatologically tested

Powered by Isolated Formulation™

Our innovative Isolated Formulation™ process allows us to formulate actives in their ideal medium, preserving their stability and efficacy. This technique ensures that you get the most out of your ingredients at every moment of use. 

Skin care that evolves with


Smarter skincare, just for you

Lesielle allows you to combine the base of your choice with the actives your skin needs. If you love your base but need to accomplish new skin care goals, combine your base with new actives—in minutes.

Our bases contain only the necessary ingredients and are completely fragrance-free. This way you can give your skin everything it needs and nothing it doesn’t.

We never use toxic ingredients, and our innovative packaging and delivery system allows us to reduce the need for preservatives.

Lesielle bases are made exclusively using dermatologically approved ingredients, proven to be effective at improving your skin’s health. Our innovative packaging and delivery system allows them to maintain their efficacy longer.

Not sure which actives to pick? We’re here to help.

FAQ. How can we help?

All actives contain 6ml of hyper-connected active (x10 times a standard concentrated serum), and have a minimum duration of 70 uses.

Of course, the bases and actives can be removed, stored and used again for 12 months.

Although this can happen in traditional cosmetics, with Lesielle you do not have this problem. This is because the active ingredients are mixed right at the moment of application and therefore do not have time to interact with each other. This is one of the major advantages of the isolated formulation. The only thing we do not recommend is to use the same ingredient twice or to combine two exfoliating actives (range imperfections) to avoid an action that is too powerful for the skin. In addition, you will have to take into account, but this is something to be learned by each person, which ingredients your skin tolerates.

Although all our actives have passed dermatological control individually, due to their high concentration, our recommendation is that you always mix the actives with a base cream in at least a 1:2 mixture.

We must begin by clarifying that there are no active ingredients that are compatible or not with sensitive skin, since it can react to any active ingredient, no matter how mild it may be. What we can say is that there are active ingredients that are more or less likely to be compatible.

You can find the degree of compatibility with sensitive skin in the data sheet of each active ingredient. In addition, you can filter in the category of active ingredients by their expected "compatibility" and, if you are in a physical store, you will find it indicated on their packaging or corresponding box.

The main properties are those in which the active ingredient is most effective. Secondary properties are properties that, as their name indicates, are also present, but are not the most outstanding properties of the active ingredient.

We recommend always testing each active and each base separately (especially on very reactive skin) to ensure that each of the elements are compatible with the skin on which they are to be used.

Lesielle recommends the following testing process:

First, test a base with each active separately. Apply to a sensitive area of the skin (behind the earlobe or on the inside of the forearm) and wait 48h to confirm good compatibility.

Then, once the actives have been found to be compatible individually, we should test their incremental mixing, increasing the number of combined actives as follows waiting after each test 48h.


Being a base B and the actives we want to test A1, A2 and A3:

B + A1 / B + A2 / B + A3.

B + A1 + A2

B + A1 + A2 + A3

At Lesielle we value the suggestions of our customers. Please write to us in our contact area so that we can take it into account for future releases.

The skincare system for an ever evolving skin, using recognized active ingredients with scientifically proven efficacy to create treatment tailored to each day's State of Skin. 

  • All rights reserved 2023