Hyaluronic Acid 2% (1.25 + 0.75%)

100 Uses

Hyaluronic Acid is a natural molecule that can hold up to 1000 times its weight in water, making it ideal for dry or dehydrated skin. It restores moisture, prevents flaking, and plumps the skin, giving you a youthful and radiant appearance. Our formula combines different molecular weight types to hydrate the skin at different levels.

Refill type: Actives (100 uses)


Targets: Dryness, Signs of Aging, Wrinkles and Fine lines

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- Increases base hydration: +0,5 levels (light and Oil-free)
- Cares for and protects the skin
- Softens the skin
- Antioxidant
- Fills wrinkles and fine lines (hydration)
- Soothes the skin

More information about this active ingredient benefits in the “Detailed info” section.

Hyaluronic acid at a concentration of 2%: A blend of hydrolyzed and high molecular weight hyaluronic acid (1.25 + 0.75) is used for superior results in different layers of the skin.

Ingredients (INCI)

Water (Aqua), Coco-caprylate, Sodium Polyacryloyldimethyl Taurate, Hydrolyzed Sodium Hyaluronate, Sodium Hyaluronate, Tocopherol, Phenoxyethanol, Ethylhexylglycerin.

Note: We continuously innovate to improve the quality of our formulas. Due to this, this ingredient list may differ from the one in the box of the products depending on time and region due to updates in the formulations.



Day & Night

Sunscreen is recommended during the day.

How: introduce it into the superior compartment of your Device to add its benefits to your personalized skincare.

Remember: your personalized skincare is made from 1 base and up to 4 actives.

pH ~4,7

Sensitive Skin: High Compatibility

Dermatologically tested

Pregnancy & Breastfeeding Safe





Discover your base and actives
Take our skin quiz

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Product Details

Data sheet

Moisturization Booster
Other features
No parabens

Detailed Info

Hyaluronic acid is a natural super-moisturizing molecule that can hold up to 1000 times its weight in water, making it ideal for dehydrated skin. It restores moisture, prevents flaking, and plumps the skin, giving you a youthful and radiant appearance. Our formula combines different molecular weight types to hydrate the skin at different levels, increasing the skin's turgor and elasticity and its ability to resist external stress.

Hyaluronic acid is also an antioxidant and forms a protective film on the skin's surface, preventing water loss and shielding the skin from environmental aggressors. It helps to maintain the skin's elasticity and firmness, reducing flakiness and the appearance of wrinkles and fine lines caused by dehydration plumping the skin from within. It also has soothing properties that calm the skin and reduce redness and irritation.

Hyaluronic acid smooths and softens the skin texture, reducing roughness.

Hyaluronic acid is suitable for all skin types, especially for dry, dehydrated, mature, or sensitive skin. It is gentle, non-irritating, and non-comedogenic. 

Lesielle's advice: we recommend you add this active ingredient to your custom skincare formula if you need to boost the moisturization of your base with a very light touch without adding oil to the skin. If you prefer to boost it with an oily or more nourishing touch, you can use the Argan oil refill

This formula is powered by our recognized Lesielle's Isolated Formulation.

You can select your active ingredients in 2 ways:

Option 1 (recommended), Take our quiz. This is the most advanced solution because it takes into account multiple factors like your lifestyle, concerns, skin type, and even active ingredient synergies.

Option 2, Select yourself. If you have some experience with skincare, you may like to decide by yourself. In this case, consider reading each active ingredient product page to get supplementary information about its properties. 
If you are starting in skincare but you like a DIY custom skincare approach, we have created a decision-tree guide to orientate you: Actives Selection Guide.pdf

NOTE: This decision tree is a simplified selection process approach. If you want the best results, we recommend you do our quiz or study the properties of the active ingredient and select the ones that, in combination (each active can have multiple effects), address your concerns in the most effective and complete way.

When to Use


Day & Night
Sunscreen is recommended during the day.

Step 1: Cleanse your skin (ideally with a non-ionic cleanser)

Step 2: Create a single dose and apply your freshly-made custom skincare.

Step 3: Apply sunscreen if required. Try to use an oil-free sunscreen to avoid adding extra oils to your skin (your base has already provided the correct amount).

All of Lesielle's products undergo dermatological testing to ensure their safety. However, since each person's skin is unique, it is always recommended to perform a patch test before using a new active ingredient in your customized skincare system. This is especially important if you have sensitive skin. Patch tests are a simple way to ensure that your skin does not have any adverse reactions to a new product.

Here's how to perform the patch test:

1. Apply a small amount of the product to your forearm.

2. Wait for 24 hours.

3. If you experience any redness, irritation, or burning sensation during the test, discontinue the use of the product and switch to an alternative solution.


Reduces Wrinkles and Expression Lines

Enhances Hydration

Non-Greasy and Light touch Hydration 

Protects the Skin


Scientifically proven, customer approved

Product Reviews / Q&A

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All actives contain 6ml of hyper-connected active (x10 times a standard concentrated serum), and have a minimum duration of 100 uses.

Of course, the bases and actives can be removed, stored and used again for 12 months.

Although this can happen in traditional cosmetics, with Lesielle you do not have this problem. This is because the active ingredients are mixed right at the moment of application and therefore do not have time to interact with each other. This is one of the major advantages of the isolated formulation. The only thing we do not recommend is to use the same ingredient twice or to combine two exfoliating actives (range imperfections) to avoid an action that is too powerful for the skin. In addition, you will have to take into account, but this is something to be learned by each person, which ingredients your skin tolerates.

Although all our actives have passed dermatological control individually, due to their high concentration, our recommendation is that you always mix the actives with a base cream in at least a 1:2 mixture.

We must begin by clarifying that there are no active ingredients that are compatible or not with sensitive skin, since it can react to any active ingredient, no matter how mild it may be. What we can say is that there are active ingredients that are more or less likely to be compatible.

You can find the degree of compatibility with sensitive skin in the data sheet of each active ingredient. In addition, you can filter in the category of active ingredients by their expected "compatibility" and, if you are in a physical store, you will find it indicated on their packaging or corresponding box.

The main properties are those in which the active ingredient is most effective. Secondary properties are properties that, as their name indicates, are also present, but are not the most outstanding properties of the active ingredient.

We recommend always testing each active and each base separately (especially on very reactive skin) to ensure that each of the elements are compatible with the skin on which they are to be used.

Lesielle recommends the following testing process:

First, test a base with each active separately. Apply to a sensitive area of the skin (behind the earlobe or on the inside of the forearm) and wait 48h to confirm good compatibility.

Then, once the actives have been found to be compatible individually, we should test their incremental mixing, increasing the number of combined actives as follows waiting after each test 48h.


Being a base B and the actives we want to test A1, A2 and A3:

B + A1 / B + A2 / B + A3.

B + A1 + A2

B + A1 + A2 + A3

At Lesielle we value the suggestions of our customers. Please write to us in our contact area so that we can take it into account for future releases.

Powered by Isolated Formulation™

Our innovative Isolated Formulation™ process allows us to formulate actives in their ideal medium, preserving their stability and efficacy. This technique also allows us to achieve up to 10x higher concentration than traditional skincare, ensuring you get the most out of your ingredients at every moment.

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Complete your custom skin care system

Moisturize, nourish, and condition your skin with premium oils and humectants. Choose a base that best matches to your skin type and desired  moisturization level

Customize your treatment and target specific concerns. Lesielle refills contain up to 10x the highest concentrated active ingredients powered by Isolated Formulation ™ and protected by airless technology.

Get personalized skincare at the touch of a button. Place the base and up to 4 actives in your device and make a fresh dose of face cream when you need it!


Don't you know what Base and Actives you need?
Do not worry. Take our skin quiz.

Not sure which actives to pick? We’re here to help.

The skincare system for an ever evolving skin, using recognized active ingredients with scientifically proven efficacy to create treatment tailored to each day's State of Skin. 

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